Vascular remodeling in the circulations of the lung.

Invited Review HIGHLIGHTED TOPIC Lung Growth and Repair Vascular remodeling in the circulations of the lung

Mitzner, Wayne, and Elizabeth M. Wagner. Vascular remodeling in the circulations of the lung. J Appl Physiol 97: 1999–2004, 2004; doi:10.1152/ japplphysiol.00473.2004.—The lung is unique in its double sources of perfusion from the pulmonary and systemic circulations. One striking difference between the two circulations is the capacity for angiogenesis. The bronchial circulation has a capacity t...

Metalloproteinases, Mechanical Factors and Vascular Remodeling

Chronic increases in arterial blood flow elicit an adaptive response of the arterial wall, leading to vessel enlargement and reduction in wall shear stress to physiological baseline value. Release of nitric oxide from endothelial cells exposed to excessive shear is a fundamental step in the remodeling process, and potentially triggers a cascade of events, including growth factor induction and m...

The Impacts Of The Press Subsidies On Their Circulations, In Iran

Quantitative evaluation of hemodynamic parameters during acute alveolar hypoxia and hypercapnia in the isolated ventilated-perfused rabbit lung

Introduction: Acute respiratory disorders such as obstructive pulmonary diseases and hypoventilation may lead to alveolar hypoxia and hypercapnia which their effects on pulmonary vascular beds are controversial. The aim of this study was to establish the isolated perfused lung setup and investigate the effects of alveolar hypoxia and hypercapnia on pulmonary vascular resistance. Methods: White ...

Pulmonary Vascular Tangle: Unusual Cause of Hemoptysis

Pulmonary vascular malformation is an unusual cause of hemoptysis. These abnormal vascular communications between pulmonary circulations or between pulmonary and systemic circulations can result in significant dyspnea, hemoptysis and hypoxemia. Pulmonary vascular malformations can take various forms. Here we present a case of an abnormal collection of thrombosed arteries and veins, without the ...